PURPOSE: evaluate the efficacy of positron emission tomography (PET) / computerized tomography (CT) in differentiating benign from malignant solitary pulmonary nodules (SPNs).
METHODS: 209 patients, who were diagnosed with SPN were evaluated.
RESULTS: 62% of the solitary nodules were benign and 38% malignant. The mean SUVmax value for the benign SPNs was 2.1 ± 3.3 compared to 7.4 ± 5.7 for the malignant SPNs. A positive correlation was found between the nodule diameter and risk for malignancy. A SUVmax value of 4 was found to have the best sensitivity and specificity.
CONCLUSION: PET/CT was shown to be an accurate method in the differential diagnosis of benign from malignant solitary pulmonary nodules.
J BUON. 2013 Oct-Dec;18(4):935-41